NCL’s Director, Scott McNeil, recently published a Correspondence article in Nature Reviews Materials. “Evaluation of nanomedicines: Stick to the basics”, was written in response to another recent Nature Reviews Materials article, Wilhelm, et al, Nature Reviews Materials, 2016, 1, 16014. The Wilhelm, et al. article provides a retrospective analysis of nanoparticle drug delivery to tumors by measuring the amount of nanoparticle carrier detected in the tumor. McNeil’s response article provides an explanation on why this is not a good measure of nanoparticle success and why traditional measures of PK are far more relevant.
You can read the full article here:
Nature Reviews Materials, 2016, 1, 16073.