About the NCL
Mission - Cancer Nanotechnology Plan - Management & Administration
Staff - Facilities - Career Opportunities
Cancer Nanotechnology Plan (CaNanoPlan)
To help meet the goal of eliminating death and suffering due to cancer, the National Cancer Institute (NCI) is engaged in a concerted effort to harness the power of nanotechnology to radically change the way we diagnose, treat, and prevent cancer. Using inputs from clinicians, cancer researchers, and technologists, the NCI has developed the Cancer Nanotechnology Plan (CaNanoPlan) to meet these goals. The CaNanoPlan lays out a pathway and a set of mechanisms to facilitate nanotechnology becoming a fundamental driver of advances in cancer research.
During its development and due diligence of the CaNanoPlan, NCI noted a widespread interest among cancer researchers in overcoming significant obstacles in order to transition nanotechnology to clinical application. These obstacles centered around three common themes:
To address and overcome these barriers, the NCI established the Nanotechnology Characterization Laboratory (NCL) at its NCI-Frederick facility. The charter of the NCL is to perform the pre-clinical characterization of nanomaterials and to facilitate the development of nanomaterials intended for clinical use. Focused development and pre-clinical testing of new technologies by the NCL will facilitate entry of these products into clinical trials, and this will directly affect the number of new diagnostic and treatment strategies that reach the market, i.e., new drug approval.
NCL resources and activities will be prioritized to influence, inform, and accelerate the research and pre-clinical test phases for drug and device development, as shown in the timeline diagram in Figure 1. The NCL’s focus on the translational phase offers a supportive method for introducing and evaluating new mechanisms for accelerating test phases, improving and defining methods, and introducing novel nanotechnology strategies into clinical trials.
Download the PDF to learn more about the CaNanoPlan.
A Service of the National Cancer Institute